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Yousef Zakharia Selected Research

1-methyltryptophan

1/2021Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma.
1/2018Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer.

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Yousef Zakharia Research Topics

Disease

37Neoplasms (Cancer)
11/2022 - 08/2014
21Renal Cell Carcinoma (Grawitz Tumor)
07/2022 - 01/2015
18Melanoma (Melanoma, Malignant)
12/2021 - 01/2017
14Carcinoma (Carcinomatosis)
11/2022 - 12/2018
7Neoplasm Metastasis (Metastasis)
10/2022 - 02/2018
5Disease Progression
07/2022 - 01/2019
4Prostatic Neoplasms (Prostate Cancer)
01/2021 - 01/2020
3Autoimmune Diseases (Autoimmune Disease)
06/2021 - 10/2016
2Hypoxia (Hypoxemia)
05/2022 - 12/2018
2Urinary Bladder Neoplasms (Bladder Cancer)
03/2022 - 01/2022
2Urologic Neoplasms (Urological Cancer)
01/2022 - 01/2020
2Fatigue
01/2022 - 10/2017
2Diarrhea
01/2022 - 06/2021
2Brain Neoplasms (Brain Tumor)
12/2021 - 03/2021
2Lung Neoplasms (Lung Cancer)
06/2021 - 10/2018
2Breast Neoplasms (Breast Cancer)
05/2011 - 03/2011
1Virus Diseases (Viral Diseases)
02/2022
1COVID-19
02/2022
1Cough
01/2022
1Anemia
01/2022
1Dyspnea (Shortness of Breath)
01/2022
1Rheumatoid Arthritis
06/2021
1Bites and Stings (Sting)
06/2021
1Drug Eruptions (Drug Eruption)
06/2021
1Hypothyroidism
06/2021
1Joint Diseases (Joint Disease)
06/2021
1Poliomyelitis (Polio)
06/2021

Drug/Important Bio-Agent (IBA)

16Immune Checkpoint InhibitorsIBA
11/2022 - 01/2017
11pembrolizumabIBA
07/2022 - 10/2016
8Biomarkers (Surrogate Marker)IBA
01/2022 - 02/2018
5SeleniumIBA
05/2022 - 02/2018
5Cisplatin (Platino)FDA LinkGeneric
01/2022 - 12/2018
4Pharmaceutical PreparationsIBA
03/2022 - 01/2019
4EnzymesIBA
01/2022 - 01/2018
4Axitinib (AG 013736)IBA
01/2022 - 01/2015
4IpilimumabIBA
06/2021 - 03/2017
3MicroRNAs (MicroRNA)IBA
05/2022 - 02/2018
3Tyrosine Kinase InhibitorsIBA
01/2022 - 01/2017
3CreatinineIBA
01/2022 - 10/2017
3Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2022 - 01/2019
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2021 - 01/2015
3NivolumabIBA
12/2020 - 01/2017
2VaccinesIBA
02/2022 - 01/2018
2DNA (Deoxyribonucleic Acid)IBA
01/2022 - 01/2020
2erdafitinibIBA
01/2022 - 01/2019
2cabozantinibIBA
12/2021 - 01/2019
2Tryptophan (L-Tryptophan)FDA Link
10/2021 - 01/2018
2Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
10/2021 - 01/2021
2RNA (Ribonucleic Acid)IBA
10/2021 - 01/2021
2talimogene laherparepvecIBA
06/2021 - 01/2019
2InterferonsIBA
06/2021 - 12/2020
2AlbuminsIBA
01/2021 - 10/2020
2atezolizumabIBA
01/2021 - 12/2018
2PlatinumIBA
01/2021 - 12/2018
21-methyltryptophanIBA
01/2021 - 01/2018
2cyclopropapyrroloindoleIBA
01/2021 - 01/2020
2AndrogensIBA
01/2021 - 01/2020
2AntioxidantsIBA
05/2020 - 02/2018
2Biological ProductsIBA
01/2020 - 01/2018
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2019 - 01/2017
1Sunitinib (Sutent)FDA Link
07/2022
1Protein Isoforms (Isoforms)IBA
05/2022
1Immunoconjugates (Immunoconjugate)IBA
03/2022
1enfortumab vedotinIBA
03/2022
1sapanisertibIBA
01/2022
1Mechanistic Target of Rapamycin Complex 1IBA
01/2022
1eribulinFDA Link
01/2022
1MTOR InhibitorsIBA
01/2022
1avelumabIBA
01/2022
1Glutamine (L-Glutamine)FDA Link
01/2022
1GlutaminaseIBA
01/2022
1Glucose (Dextrose)FDA LinkGeneric
01/2022
1EverolimusFDA Link
01/2022
1Chemokine CXCL10IBA
12/2021
1Toll-Like Receptor 9IBA
12/2021
1Agammaglobulinaemia Tyrosine KinaseIBA
10/2021
1Membrane Proteins (Integral Membrane Proteins)IBA
10/2021
1CalciumIBA
06/2021
1MGN1703IBA
06/2021
1bempegaldesleukinIBA
06/2021
1TTI-621IBA
06/2021
1daromunIBA
06/2021
1tilsotolimodIBA
06/2021
1sotigalimabIBA
06/2021
1poly ICLCIBA
06/2021
1vadimezanIBA
06/2021
1tofacitinibIBA
06/2021
1Infliximab (Remicade)FDA Link
06/2021
1Antimicrobial PeptidesIBA
06/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
06/2021
1AntibodiesIBA
06/2021
1Cytidine Monophosphate (CMP)IBA
06/2021
1Interleukin-2 (IL2)IBA
06/2021
1Vinblastine (Vinblastine Sulfate)FDA Link
06/2021
1Interleukin-12 (IL 12)IBA
06/2021

Therapy/Procedure

36Therapeutics
11/2022 - 08/2014
17Immunotherapy
01/2022 - 08/2014
10Drug Therapy (Chemotherapy)
01/2022 - 07/2014
3Radiotherapy
11/2022 - 01/2018
2Adjuvant Chemotherapy
01/2022 - 01/2019